Table II.

Toxicity prediction of nitrogenous heterocyclic compounds.

Compound	Mouse female NTP prediction	Mouse male NTP prediction	Rat female NTP prediction	Rat male NTP prediction	Ames prediction	Skin irritancy	Ocular irritancy	Aerobic biodegradability prediction
N1	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Mutagen	None	Mild	Non-degradable
N2	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N3	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N4	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N5	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N6	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Mutagen	None	Mild	Non-degradable
N7	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Mutagen	None	Mild	Non-degradable
N8	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Mutagen	None	Mild	Non-degradable
N9	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Mutagen	None	Mild	Non-degradable
N10	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N11	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable
N12	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-carcinogen	Non-mutagen	None	Mild	Non-degradable

NTP, National Toxicology Program.