. 2018 Jun 4;16(2):2237–2242. doi: 10.3892/ol.2018.8880

Table III.

Univariate and Multivariate Cox regression analyses of patient survival.

	Univariate			Multivariate

Variable	HR	95% CI	P-value	HR	95% CI	P-value
Sex (male vs. female)	0.709	0.464–1.085	0.113	0.821	0.277–1.438	0.383
Age (≥40 years vs. <40 years)	2.506	1.623–3.871	<0.001^a	2.170	0.467–3.909	0.001^a
KPS (≥70 vs. <70)	0.162	0.787–4.181	0.162	0.950	0.023–2.751	0.909
Extent of resection (total vs. subtotal)	1.389	0.884–2.182	0.154	1.552	0.345–3.320	0.071
Tumor location (supratentorial vs. infratentorial)	0.295	0.093–0.935	0.038	0.697	0.991–12.140	0.557
WHO grade (T2/T3/T4)	1.828	1.424–2.346	<0.001^a	1.573	1.565–6.090	0.001^a
MMP-26 (low vs. high)	2.600	1.657–4.080	<0.001^a	1.865	0.352–2.360	0.009^a

P<0.05 was considered significant. KPS, Karnofsky performance status; WHO, World Health Organization; HR, hazard ratio; CI, confidence interval; MMP, matrix metalloproteinase.