Table I.
Analysis of the candidate genes with univariate and multivariate Cox regression.
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Gene | HR | 95% CI | P-value | HR | 95% CI | P-value |
| TMEM109 | 1.50 | 1.50–1.30 | <0.001 | 1.30 | 1.08–1.57 | 0.005 |
| AHNAK | 1.40 | 1.40–1.20 | <0.001 | 1.14 | 0.95–1.37 | 0.152 |
| BCL2L14 | 0.76 | 0.76–0.68 | <0.001 | 0.82 | 0.73–0.93 | 0.003 |
| AOC2 | 0.79 | 0.79–0.69 | <0.001 | 1.01 | 0.85–1.2 | 0.890 |
| ZNF230 | 0.73 | 0.73–0.62 | <0.001 | 0.81 | 0.69–0.96 | 0.015 |
| AGER | 0.77 | 0.77–0.68 | <0.001 | 0.88 | 0.75–1.04 | 0.133 |
| APOL2 | 0.73 | 0.73–0.63 | <0.001 | 0.78 | 0.67–0.9 | 0.001 |
HR, hazard ratio; CI, confidence interval; TMEM109, transmembrane protein 109; BCL2L14, BCL2-like 14; AOC2, amine oxidase, copper containing 2; ZNF230, zinc finger protein 230; AGER, advanced glycation end-product specific receptor; APOL2, apolipoprotein L2.