Histological features of the resected intestine and villus height and weight-to-length ratio of the resected specimen according to groups. Hematoxylin and eosin staining was performed in samples from the (A) Control, (B) 5-FU, (C) 5-FU + UDCA (10 mg/kg/day), (D) 5-FU + UDCA (100 mg/kg/day) and (E) 5-FU + UDCA (500 mg/kg/day) groups. Histological examination of the jejunal villi and crypts are presented (magnification, ×100). (F) Villus height and (G) W/L ratio of the resected jejunal specimen were measured. Data are shown as the mean ± standard deviation. *P<0.05 vs. the 5-FU group. W/L, weight-to-length; 5-FU, 5-fluorouracil; UDCA, ursodeoxycholic acid.