CCR7 ligand-binding function modulates BxPC-3 cell migration by regulating ANO6 expression. (A) Western blot analysis of ANO6 in OE and NC cells pretreated with or without CCL21 and U0126. GAPDH was used as a loading control. (B) Reverse transcription-quantitative polymerase chain reaction analysis of ANO6 in OE and NC cells with or without pretreatment of CCL21 and U0126. **P<0.01. CCR7, C-C motif chemokine receptor 7; CCL21, C-C motif chemokine ligand 21; ANO6, anoctamin 6; NC, blank-vector-transfected negative control; OE, CCR7-overexpressing cells.