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. 2018 Jul 2;9:1439. doi: 10.3389/fmicb.2018.01439

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Copyright © 2018 Lépine, de Wit, Oosterink, Wichers, Mes and de Vos.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of lactobacilli strains on TEER of Caco-2 cells. A 21-days differentiated Caco-2 cells were incubated with L. acidophilus W37, L. brevis W63, and L. casei W56 for 6 h. TEER was measured after 0, 1, 3, and 6 h incubation, values were normalized based on the time-point t = 0 h measurement and are expressed as delta variation compared to DMEM control for each time-point, which was set to 100%. Statistically significant difference compared to control were assessed with SPSS statistics using ANOVA followed by LSD test with ^∗p < 0.05.