Box plot results for the BRATS tumor dataset. BSE and CNN fail on this dataset. BEaST also fails when applied directly to the BRATS dataset due to spatial normalization failures. We therefore show results for BEaST* here, our modification which uses the affine registration of the PCA model first. BET shows better performance, but also exhibits outliers. ROBEX, BEaST*, MASS, and our PCA model work well on this dataset. Overall our model exhibits the best performance scores.