TABLE 3.
Multivariate Analysis of Freedom From Metastatic Failure
| Variables | Unadjusted for Propensity Score
|
Adjusted for Propensity Score
|
||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | |
| Treatment | 0.08 | 0.10 | ||||
| SRT | 1.00 | Reference group | 1.00 | Reference group | ||
| ART | 0.11 | 0.01, 1.34 | 0.15 | 0.02, 1.38 | ||
| Time from RP to RT | 1.01 | 0.98, 1.03 | 0.49 | 1.01 | 0.99, 1.03 | 0.29 |
| Seminal vesicle invasion | 0.34 | 0.22 | ||||
| No | 1.00 | Reference group | 1.00 | Reference group | ||
| Yes | 1.95 | 0.50, 7.62 | 2.20 | 0.63, 7.70 | ||
| Extracapsular extension | 0.92 | 0.74 | ||||
| No | 1.00 | Reference group | 1.00 | Reference group | ||
| Yes | 1.08 | 0.22, 5.35 | 1.31 | 0.27, 6.37 | ||
| Positive margin | 0.21 | 0.17 | ||||
| No | 1.00 | Reference group | 1.00 | Reference group | ||
| Yes | 4.20 | 0.44, 40.46 | 5.10 | 0.51, 51.25 | ||
| Gleason score | ||||||
| ≤6 | 1.00 | Reference group | 1.00 | Reference group | ||
| 7 | 0.84 | 0.15, 4.77 | 0.85 | 0.99 | 0.19, 5.06 | 0.99 |
| 8–10 | 2.42 | 0.38, 15.39 | 0.35 | 1.82 | 0.30, 11.02 | 0.52 |
| Treatment field | 0.54 | 0.7 | ||||
| Prostatic fossa | 1.00 | Reference group | 1.00 | Reference group | ||
| Prostatic fossa + pelvis | 1.42 | 0.47, 4.31 | 1.25 | 0.41, 3.76 | ||
| ADT | 0.53 | 0.1 | ||||
| No | 1.00 | Reference group | 1.00 | Reference group | ||
| Yes | 1.69 | 0.34, 8.46 | 3.01 | 0.80, 11.39 | ||
| Age | 0.98 | 0.91, 1.06 | 0.63 | 0.93 | 0.84, 1.02 | 0.11 |
ADT indicates androgen deprivation therapy; ART, adjuvant radiation therapy; CI, confidence interval; HR, hazard ratio; RP, radical prostatectomy; RT, radiation therapy; SRT, salvage radiation therapy.