. Author manuscript; available in PMC: 2018 Jul 9.

Published in final edited form as: Mol Carcinog. 2017 Jan 2;56(4):1335–1343. doi: 10.1002/mc.22595

Table 3.

Association between E2F2 genotypes and HPV-positive SCCOP recurrence in patients with SCCOP (N = 324).

Genotype	No. of recurrence/no. of patients	5-year recurrence rate	Log-rank p values	aHR¹, 95% CI
E2F2-rs6667575
GG(Ref.)	24/157	0.16	0.464	1.0
GA+AA	21/167	0.14		0.9 (0.5-1.7)
E2F2-rs3218121
GG(Ref.)	40/296	0.15	0.451	1.0
GA+AA	5/28	0.20		1.6 (0.6-4.1)
E2F2-rs2742976
GT/TT(Ref.)	41/196	0.21	<0.001	1.0
GG	4/128	0.04		0.1 (0.1-0.4)
E2F2-rs3218123
GT/TT(Ref.)	39/146	0.31	<0.001	1.0
GG	6/178	0.04		0.1 (0.0-0.2)
E2F2-rs3218148
AA(Ref.)	17/135	0.14	0.554	1.0
AG/GG	28/189	0.16		1.3 (0.7-2.5)

aHR, adjusted hazard ratio.

aHR, adjusted Hazard ratio for age, sex, ethnicity, smoking status, alcohol use status, stage, comorbidity, and treatment.

Ref: Reference group.