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. Author manuscript; available in PMC: 2018 Jul 9.
Published in final edited form as: Mol Carcinog. 2017 Jan 2;56(4):1335–1343. doi: 10.1002/mc.22595

Table 4.

Association between combined E2F2 genotypes and recurrence risk in overall and tumor HPV-positive patients with SCCOP.

Combined genotypes No. of recurrence/no. of patients 5-year recurrence rate Log-rank p values aHR1, 95% CI
All patients (N=1008)
 High risk group*(Ref.) 73/247 0.32 < 0.001 1.0
 Low risk group 108/761 0.14 0.4 (0.3-0.6)
HPV-positive SCCOP patients (N=324)
 High risk group(Ref.) 26/82 0.40 < 0.001 1.0
 Low risk group 19/242 0.08 0.2 (0.1-0.5)
*

high-risk group: individuals carrying 2-5 genotypes; Low-risk group: individuals carrying 0-1 genotype.

1

aHR, adjusted hazard ratio for age, sex, ethnicity, smoking status, alcohol use status, stage, comorbidity, and treatment.

Ref: Reference group.