Table 3.
Report of Anticholinergic Exposure at Any Wave Following Baseline
| ACB score 1 | Proportion exposed, %a | ACB score 2 | Proportion exposed, %a | ACB score 3 | Proportion exposed, % a |
|---|---|---|---|---|---|
| Alprazolam | 2.0 | Carbamazepine | 1.4 | Amitriptyline | 7.4 |
| Aripiprazole | 0.3 | Cyclobenzaprine | 12.0 | Atropine | 0.6 |
| Atenolol | 10.9 | Oxcarbazepine | 0.3 | Chlorcyclizine | 0.9 |
| Bupropion | 6.6 | Chlorpheniramine | 0.3 | ||
| Captopril | 0.3 | Clemastine | 0.3 | ||
| Cetirizine | 2.6 | Dicyclomine | 2.0 | ||
| Chlorthalidone | 0.6 | Diphenhydramine | 1.1 | ||
| Codeine | 10.6 | Diphenoxylate-Atropine | 0.6 | ||
| Colchicine | 4.3 | Doxepin | 1.1 | ||
| Diazepam | 4.0 | Hydroxyzine | 12.9 | ||
| Digoxin | 4.3 | Meclizine | 8.0 | ||
| Fentanyl | 2.6 | Nortriptyline | 1.7 | ||
| Furosemide | 24.6 | Olanzapine | 0.9 | ||
| Haloperidol | 0.3 | Oxybutynin | 10.0 | ||
| Hydralazine | 11.1 | Paroxetine | 3.1 | ||
| Isosorbide | 10.6 | Promethazine | 7.7 | ||
| Levocetirizine | 0.3 | Propantheline | 0.3 | ||
| Loperamide | 1.1 | Quetiapine | 1.7 | ||
| Loratadine | 1.4 | Scopolamine | 0.3 | ||
| Metoprolol | 42.0 | Solifenacin | 0.3 | ||
| Morphine | 3.1 | Tolterodine | 2.6 | ||
| Nifedipine | 0.6 | Trifluoperazine | 0.3 | ||
| Prednisone | 18.3 | Trihexyphenidyl | 0.3 | ||
| Ranitidine | 17.4 | ||||
| Risperidone | 1.7 | ||||
| Theophylline | 1.1 | ||||
| Trazodone | 17.1 | ||||
| Triamterene-Hydrochlorothiazide | 10.6 | ||||
| Venlafaxine | 1.4 | ||||
| Warfarin | 13.7 |
ACB = anticholinergic cognitive burden.
a
Medication use reported as proportion of all participants who used the medication at any point after baseline. Denominator for the proportion was 350.