Table 5.
Impact of tobacco, alcohol, and NSAIDs on treatment response in EoE cases
| EoE cases with follow up data (n = 86)† | |||
|---|---|---|---|
| No histologic response (n = 28) | Histologic response (n = 58) | p* | |
| NSAID use (n, %) | |||
| Not current | 26 (37) | 45 (63) | 0.08 |
| Current | 2 (13) | 13 (87) | |
| Smoking (n, %) | |||
| Never | 21 (32) | 47 (68) | 0.60 |
| Ever | 7 (39) | 11 (61) | |
| Chewing tobacco (n, %) | |||
| Ever used | |||
| No | 24 (32) | 53 (68) | 0.47 |
| Yes | 4 (44) | 5 (56) | |
| Current use | |||
| No | 26 (32) | 58 (68) | 0.05 |
| Yes | 2 (100) | 0 (0) | |
| Alcohol (n, %) | |||
| Current use | |||
| No | 9 (45) | 11 (55) | 0.19 |
| Yes | 19 (29) | 47 (71) | |
| >7 drinks per week | |||
| No | 22 (40) | 34 (60) | 0.06 |
| Yes | 6 (20) | 24 (80) | |
†nonresponders defined by ≥15 eos/hpf on esophageal biopsy; responders defined by <15 eos/hpf on esophageal biopsy;
*proportions compared with chi-square.