Table 2.
Univariate and multivariate analyses of predictive factors in HCC patients with liver resection
| Clinicopathological features | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| RR (95% CI) | P value | RR (95% CI) | P value | |
| Age, year (<50 versus ≥50) | 0.782 (0.318 - 1.726) | 0.415 | 0.651 (0.277-1.237) | 0.524 |
| Gender (Female versus Male) | 0.354 (0.075 - 1.352) | 0.361 | 0.432 (0.069 - 1.686) | 0.505 |
| HBV infection | 1.925 (0.998 - 3.399) | 0.095 | 1.729 (0.895 - 2.529) | 0.122 |
| Serum AFP level (ng/mL) (≥ 400 versus < 400) | 1.528 (0.579 - 1.981) | 0.155 | 1.338 (0.578 - 1.988) | 0.257 |
| Tumor diameter (cm) (≥ 5 versus < 5) | 1.752 (0.612 - 2.428) | 0.091 | 1.487 (0.524 - 2.197) | 0.129 |
| Liver cirrhosis | 2.110 (0.977 - 2.352) | 0.124 | 1.857 (0.769-3.272) | 0.110 |
| Edmondson-Steiner Classification (III + IV versus I + II) | 1.381 (0.485 - 1.420) | 0.095 | 1.128 (0.569 - 2.155) | 0.138 |
| Advanced TNM staging | 1.932 (1.188 - 4.460) | 0.037 | 1.799 (1.395 - 3.715) | 0.044 |
| PVTT | 2.695 (1.853 - 5.257) | 0.025 | 2.495 (1.572 - 4.913) | 0.033 |
| Intrahepatic metastases | 1.582 (1.089 - 3.228) | 0.008 | 1.399 (1.090 - 2.652) | 0.019 |
| Higher PDE4a in tumor tissue | 1.827 (1.092-3.057) | 0.008 | 1.558 (1.164 - 2.615) | 0.012 |
| MVI | 2.358 (1.398-5.037) | 0.002 | 1.988 (1.125-4.289) | 0.001 |