Table 1.
Selected baseline characteristics of the 2,318 patients with nasopharyngeal carcinoma and the groups stratified by COR-BMI score
| Characteristic | Total (n, %) | COR-BMI 0 (n, %) | COR-BMI 1 (n, %) | COR-BMI 2 (n, %) | P-value* |
|---|---|---|---|---|---|
| 2318 (100) | 537 (23.2) | 1738 (75) | 43 (1.9) | ||
| Gender | 0.185 | ||||
| Male | 2200 (94.9) | 516 (96.1) | 1645 (94.6) | 39 (90.7) | |
| Female | 118 (5.1) | 21 (3.9) | 93 (5.4) | 4 (9.3) | |
| Age (years) | 0.197 | ||||
| < 45 | 1201 (51.8) | 273 (50.8) | 900 (51.8) | 28 (65.1) | |
| ≥ 45 | 1117 (48.2) | 264 (49.2) | 838 (48.2) | 15 (34.9) | |
| Smoking | 0.021 | ||||
| Yes | 1614 (69.6) | 362 (67.4) | 1216 (70) | 36 (83.7) | |
| No | 704 (30.4) | 175 (32.6) | 522 (30) | 7 (16.3) | |
| Family history of NPC | 0.672 | ||||
| Yes | 79 (3.4) | 21 (3.9) | 56 (3.2) | 2 (4.7) | |
| No | 2239 (96.6) | 516 (96.1) | 1682 (96.8) | 41 (95.3) | |
| Stage (7th) | 0.328 | ||||
| I - II | 281 (12.1) | 75 (14) | 201 (11.6) | 5 (11.6) | |
| III - IVAB | 2037 (87.9) | 462 (86) | 1537 (88.4) | 38 (88.4) | |
| T category | 0.978 | ||||
| T1 - T2 | 580 (25) | 136 (25.3) | 433 (24.9) | 11 (25.6) | |
| T3 - T4 | 1738 (75) | 401 (74.7) | 1305 (75.1) | 32 (74.4) | |
| N category | 0.345 | ||||
| N0 - N1 | 1050 (45.3) | 254 (47.3) | 780 (44.9) | 16 (37.2) | |
| N2 - N3 | 1268 (54.7) | 283 (52.7) | 958 (55.1) | 27 (62.8) | |
| Radiotherapy technique | 0.223 | ||||
| 2DRT/3DCRT | 527 (22.7) | 136 (25.3) | 380 (21.9) | 11 (25.6) | |
| IMRT | 1791 (77.3) | 401 (74.7) | 1358 (78.1) | 32 (74.4) | |
| Treatment | 0.235 | ||||
| RT | 561 (24.2) | 117 (21.8) | 431 (24.8) | 13 (30.2) | |
| CT + RT | 1757 (75.8) | 420 (78.2) | 1307 (75.2) | 30 (69.8) | |
| EBV-DNA (copies mL-1) | 0.364 | ||||
| < 2,560 | 1156 (49.9) | 281 (52.3) | 852 (49) | 23 (53.5) | |
| ≥ 2,560 | 1162 (50.1) | 256 (47.7) | 886 (51) | 20 (46.5) | |
| Outcomes | |||||
| Death | 0.019 | ||||
| Yes | 394 (17) | 78 (14.5) | 303 (17.4) | 13 (30.2) | |
| No | 1924 (83) | 459 (85.5) | 1435 (82.6) | 30 (69.8) | |
| Distant metastasis | 0.214 | ||||
| Yes | 647 (27.9) | 139 (25.9) | 492 (28.3) | 16 (37.2) | |
| No | 1671 (72.1) | 398 (74.1) | 1246 (71.7) | 27 (62.8) |
Abbreviations: COR-BMI = Combination of red blood cell distribution width and body mass index; COR-BMI 0 (RDW ≤ 13.55 and BMI ≥ 25 kg/m2); COR-BMI 1 (RDW ≤ 13.55 and BMI < 18.5 or 18.5 ≤ BMI < 25; RDW > 13.55 and 18.5 ≤ BMI < 25 or BMI ≥ 25); COR-BMI 2 (RDW > 13.55 and BMI < 18.5).; 2DRT: two-dimensional radiotherapy; 3DCRT: three-dimensional conformal radiotherapy; IMRT: intensity-modulated radiation therapy; RT: radiotherapy; CT: chemotherapy.
* Chi-square test.