Table 1.
Characteristics of studies in this meta-analysis
| Study | Year | Country | Cancertype | Sample size | Cut-off | AGR level | Survival analysis | Multivariate analysis | Hazard ratios (95% CI) | Follow-up (month) | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lowlevel | Low with LNM | Highlevel | High with LNM | ||||||||||
| Zhang J | 2016 | China | HCC | 105 | 1.18 | 25 | 8 | 80 | 10 | OS | Yes | 5.17 (2.72-9.82) | 80 (total) |
| Zhang F | 2016 | China | ESCC | 458 | 1.3 | 41 | 22 | 417 | 194 | OS | Yes | 1.318 (0.88-1.973) | 46.8 (median) |
| Chen Z | 2017 | China | RCC | 416 | 1.22 | 72 | 5 | 344 | 5 | OS | Yes | 6.529 (3.036-14.042) | 69.2 (median) |
| Zhang B | 2015 | China | UTUC | 187 | 1.45 | 78 | 3 | 109 | 3 | OS | Yes | 2.12 (1.33-3.69) | 92 (total) |
| Deng Y | 2016 | China | HCC | 172 | 1.48 | 105 | N/A | 67 | N/A | OS | Yes | 2.488 (1.447-4.292) | 120 (total) |
| Bi X | 2016 | China | NKTCL | 331 | 1.3 | 117 | 58 | 214 | 61 | OS | Yes | 1.74 (1.18-2.56) | 156 (total) |
| Du X | 2014 | China | NPC | 694 | 1.4 | 226 | 172 | 468 | 326 | OS | Yes | 1.439 (1.038-1.946) | 88 (median) |
| He X | 2017 | China | RCC | 895 | 1.47 | 371 | 47 | 524 | 19 | OS | Yes | 1.587 (1.075-2.326) | 69.68 (median) |
| Shibutani M | 2015 | Japan | CC | 66 | 1.254 | 32 | N/A | 34 | N/A | OS | Yes | 2.247 (1.069-4,722) | 60 (total) |
| Zhou T | 2016 | China | SCLC | 379 | 1.29 | 91 | N/A | 288 | N/A | OS | Yes | 1.43 (1.05-1.95) | 15.06 (median) |
| Fujikawa H | 2017 | Japan | CC | 248 | 1.32 | N/A | N/A | N/A | N/A | OS | Yes | 2.67 (1.33-5.50) | 49.7 (median) |
| Oki S | 2016 | Japan | EC | 112 | 1.41 | N/A | N/A | N/A | N/A | OS | Yes | 0.75 (0.31-1.76) | 24.9 (median) |
| Xu W | 2017 | China | GB | 166 | 1.75 | 103 | N/A | 63 | N/A | OS | Yes | 1.27 (1.021-2.801) | 14 (median) |
| Toiyama Y | 2016 | Japan | GC | 384 | 1.3793 | N/A | N/A | N/A | N/A | OS | Yes | 1.537 (0.890-2.654) | 47.6 (median) |
RCC: renal cell carcinoma, CC: colon cancer, HCC: hepatocellular carcinoma, ESCC: esophageal squamous cell carcinoma, UTUC: upper tract urothelial carcinoma, NKTCL: natural killer/T-cell lymphoma, NPC: nasopharyngeal carcinoma, SCLC: small cell lung cancer; EC: esophageal cancer, GB: glioblastoma, GC: gastric cancer; N/A: not available