Table 3.
Correlations between CD163+ macrophages and clinicopathological features in BLBC by their locations
| CD163 in TS | CD163 in TN | |||||||
|---|---|---|---|---|---|---|---|---|
| Variables | N | High, n (%) | rs | P | High, n (%) | rs | P | |
| Age, years | -0.380 | <0.001 | -0.100 | 0.159 | ||||
| < 50 | 98 | 68(69.4) | 54(55.1) | |||||
| ≥50 | 102 | 32(31.4) | 46(45.1) | |||||
| Tumor size, cm | 0.284 | <0.001 | 0.022 | 0.759 | ||||
| ≤2 | 60 | 17(28.3) | 29(48.3) | |||||
| > 2 | 140 | 83(59.3) | 71(50.7) | |||||
| Histological Grade (SBR) | 0.581 | <0.001 | -0.020 | 0.778 | ||||
| Grade 1 | 0 | 0 | 0 | |||||
| Grade 2 | 94 | 18(19.1) | 48(51.1) | |||||
| Grade 3 | 106 | 82(77.4) | 52(49.1) | |||||
| Lymph node metastasis | 0.029 | 0.688 | 0.011 | 0.872 | ||||
| Negative | 123 | 58(47.2) | 62(50.4) | |||||
| 1 to 3 | 43 | 29(67.4) | 19(44.2) | |||||
| 4to 9 | 22 | 8(36.4) | 11(50.0) | |||||
| 10 or more | 12 | 5(41.7) | 8(66.7) | |||||
| Recurrence (5 years) | 0.145 | 0.041 | 0.072 | 0.308 | ||||
| No | 156 | 72(46.2) | 75(48.1) | |||||
| Yes | 44 | 28(63.6) | 25(56.8) | |||||
|
Breast cancer mortality
(5 years) |
0.178 | 0.011 | 0.051 | 0.473 | ||||
| No | 162 | 74(45.7) | 79(48.8) | |||||
| Yes | 38 | 26(68.4) | 21(55.3) | |||||
TS, tumor stroma; TN, tumor nest; BLBC, basal-like breast cancer.