Table 5.
Multivariate Cox regression analyses for RFS and OS of BLBC
| Variables | OS | RFS | |||||
|---|---|---|---|---|---|---|---|
| HR | 95%CI | P | HR | 95%CI | P | ||
| Age (<50 vs.≥50) | 2.463 | 0.184-0.897 | 0.026 | 2.032 | 0.244-0.991 | 0.047 | |
| Tumor size, cm (≤2 vs. >2) | 3.020 | 1.030-8.854 | 0.044 | 2.581 | 1.192-5.588 | 0.016 | |
| Histological Grade (II vs. III) | 1.435 | 0.647-3.180 | 0.374 | 1.367 | 0.722-2.588 | 0.338 | |
| Lymph node stage (N0 vs. N1-3) | 1.748 | 1.311-2.331 | <0.001 | 1.836 | 1.468-2.297 | <0.001 | |
| Radiotherapy (no vs. yes) | 1.328 | 0.938-1.882 | 0.110 | 1.190 | 0.906-1.564 | 0.212 | |
| CD68+ in TS (low vs. high) | 1.850 | 0.796-4.298 | 0.153 | 1.250 | 0.666-2.345 | 0.487 | |
| CD163+ in TS (low vs. high) | 3.427 | 1.368-8.587 | 0.009 | 4.304 | 1.994-9.286 | <0.001 | |
BLBC, basal-like breast cancer; TS, tumor stroma; OS: overall survival; RFS: recurrence-free survival; HR: hazard ratio; CI: confidence interval.