Table 2.
Univariate and multivariate analyses of prognostic factors for overall survival in HCC patients who had undergone TACE in the present study.
| Variable | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| Log-rank χ2 | P value | B | SE | HR | 95% CI | P value | |
| Age, years (> 50/≤ 50) | 1.885 | 0.170 | |||||
| Ascites (yes/no) | 0.719 | 0.396 | |||||
| Laboratory parameters | |||||||
| ALP, U/L (> 200/≤ 200) | 0.952 | 0.329 | |||||
| ALB, (> 36/≤ 36) | 2.039 | 0.153 | |||||
| AFP, ng/dL (> 400/≤ 400) | 6.492 | 0.011* | ND | ||||
| BUN, mmol/L (> 8.9/≤ 8.9) | 3.368 | 0.066 | |||||
| TBIL, mg/dL (≥ 3/< 3) | 0.128 | 0.721 | |||||
| TNM-T category | 12.369 | 0.006* | |||||
| 1 | ND | ||||||
| 2 | |||||||
| 3 | |||||||
| 4 | |||||||
| PVTT (yes/no) | 30.412 | < 0.001* | 0.635 | 0.133 | 1.887 | 1.455 to 2.448 | < 0.001 |
| Lymph node metastasis (yes/no) | 0.611 | 0.435 | |||||
| Distant metastasis (yes/no) | 13.941 | < 0.001* | 0.646 | 0.218 | 1.908 | 1.245 to 2.927 | 0.003 |
| Antivirus treatments (yes/no) | 0.202 | 0.653 | |||||
| Times of TACE (> 2/≤ 2) | 6.863 | 0.009* | 0.385 | 0.133 | 1.470 | 1.133 to 1.905 | 0.004 |
AFP: alpha fetoprotein; BUN: blood urea nitrogen; ALB: albumin; TBIL: total bilirubin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALP: alkaline phosphatase; ALBI: albumin-bilirubin grade; TNM: tumor-node-metastasis; TACE: transcatheter arterial chemoembolization; PVTT: portal vein tumor thrombus; ND: not detected. * Variables with P value less than 0.05 were entered into multivariate analysis.