Table 2.
Univariate Cox proportional hazards analysis of NOTCH gene expression and overall survival (TCGA) or relapse free survival (GSE39582) for patients with colorectal cancer.
| TCGA | GSE39582 | |||
|---|---|---|---|---|
| Factor | HR (95% CI) | P | HR (95% CI) | P |
| NOTCH1 | 0.922(0.638-1.332) | 0.667 | 0.960(0.622-1.483) | 0.856 |
| NOTCH2 | 0.979(0.692-1.385) | 0.907 | 1.471(0.976-2.217) | 0.065 |
| NOTCH3 | 1.312(1.065-1.617) | 0.011 | 1.982(1.435-2.737) | <0.001 |
| NOTCH4 | 1.378(1.057-1.796) | 0.018 | 2.995(1.650-5.435) | <0.001 |
| JAG1 | 1.102(0.865-1.403) | 0.431 | 0.847(0.639-1.122) | 0.248 |
| JAG2 | 1.050(0.781-1.412) | 0.748 | 0.832(0.656-1.055) | 0.129 |
| DLL1 | 1.106(0.867-1.413) | 0.417 | 0.968(0.668-1.402) | 0.865 |
| DLL3 | 1.065(0.921-1.231) | 0.397 | 2.044(1.012-4.130) | 0.046 |
| DLL4 | 1.570(1.061-2.324) | 0.024 | 1.648(0.990-2.742) | 0.055 |
Abbreviation: CI, confidence interval; HR, hazard ratio
Bold type indicates statistical significance