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. 2018 Jun 6;9(13):2317–2326. doi: 10.7150/jca.25427

Figure 1.

Figure 1

The expression and prognosis of miR-1296 in CRC. (A) MiR-1296 expression was detected in 80 pairs of CRC and tumor-adjacent tissues. qRT-PCR data showed that the expression of miR-1296 was prominently higher in CRC tissues compared to adjacent normal tissues. P<0.05 by Student's t-test. (B) The level of miR-1296 in five CRC cell lines (HCT116, Caco2, HT29, SW620 and SW480) was up-regulated as compared with human intestinal epithelial cell line (HIEC). n=three independent experiments, *P<0.05 by one-way ANOVA. (C) Different subgroups (low/high miR-1296 expression) were plotted according to the median expression of miR-1296 in the cohort. CRC patients with high miR-1296 level had a significant shorter overall survival compared to those with low miR-1296 level. P<0.05 by Log-rank test.