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. 2018 Jun 8;14(9):1081–1089. doi: 10.7150/ijbs.24692

Figure 1.

Figure 1

Silencing of SMC1A reduces HepG2 and Bel7402 cell proliferation and migration. (A) Interference efficiency of SMC1A by shRNA or negative control (NC; scrambled shRNA) in HepG2 and Bel7402 cells by western blot analysis. The effect of SMC1A knockdown on HepG2 and Bel7402 cell proliferation was performed using Cell Counting Kit-8, ***P< 0.001 (B) and PCNA protein level expression,***P<0.001, *P<0.05 (C). Transwell assay, ***P<0.001 (D) and expression of MMP9 protein level, **P<0.01, *P<0.05 (E) were used to detect the migration of SMC1A knockdown in HepG2 and Bel7402 cells. Scale bar 50 μm. Data were expressed as means ± SD.