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Effect of KC-derived MMP9 on ratio of MMPs/TIMPs. The ratios of (A) MMP9/TIMP1, (B) MMP13/TIMP1, (C) MMP2/TIMP2 and (D) MMP14/TIMP2 were calculated based on MMPs and TIMP mRNA levels. Data were expressed as mean ± standard deviation. n=5, *p<0.05 (compared with control); ^p<0.05 (compared with the treatment by KCs from MMP9-/- animals). WT, treatment with KCs from wild type mice; KO, treatment with KCs from matrix metalloproteinase-9 deficiency mice.
