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. 2018 Jun 25;2018:9365464. doi: 10.1155/2018/9365464

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Copyright © 2018 Morouj Ismail et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of treatments on liver histology. Photomicrographs of liver sections stained by H&E. (a) Normal rat showing normal liver architecture. (b) AIA untreated rat showing moderate portal inflammation (+++) and neutrophil infiltration (black arrow). (c, d) MTX-treated AIA rat shows distortion of liver architecture with severe portal inflammation (++++) and neutrophil infiltration (black arrow), vascular congestion (aster), and multinucleation (cross). (e) Sesame oil-treated AIA rat shows mild portal inflammation (++) with neutrophil infiltration (arrow). (f) Δ9-THC/sesame oil-treated AIA rat shows minimal portal inflammation (+) with neutrophil infiltration (arrow) and normal liver architecture.