Table 3.

Summary of GO terms for differentially expressed genes between model and control groups.

Ontology source	GO ID	GO term	Term P value
Biological process	GO: 0034616	Response to laminar fluid shear stress	1.07E − 04
	GO: 0006525	Arginine metabolic process	4.12E − 04
	GO: 0034405	Response to fluid shear stress	2.18E − 03
	GO: 0021885	Forebrain cell migration	1.63E − 02
	GO: 0035914	Skeletal muscle cell differentiation	1.75E − 02
	GO: 0006094	Gluconeogenesis	1.81E − 02
Cellular component	GO: 0022625	Cytosolic large ribosomal subunit	1.19E − 05
	GO: 0015934	Large ribosomal subunit	1.53E − 04
	GO: 0022626	Sytosolic ribosome	2.36E − 04
	GO: 0031941	Filamentous actin	1.19E − 03
	GO: 0005881	Cytoplasmic microtubule	8.66E − 03
	GO: 0005746	Mitochondrial respiratory chain	1.18E − 02
Molecular function	GO: 0005520	Insulin-like growth factor binding	6.88E − 04
	GO: 0016879	Ligase activity, forming carbon-nitrogen bonds	7.94E − 03
	GO: 0033613	Activating transcription factor binding	9.60E − 03

15 GO terms are significantly enriched by the 171 changed genes after control group loaded by high glucose.