Table 4.

Summary of GO terms for differentially expressed genes between drug and model groups.

Ontology source	GO ID	GO term	Term P value
Biological process	GO: 1902600	Hydrogen ion transmembrane transport	2.60E − 04
	GO: 0070646	Protein modification by small protein removal	6.99E − 04
Cellular component	GO: 0005732	Small nucleolar ribonucleoprotein complex	3.34E − 06
	GO: 0005685	U1 snRNP	1.47E − 03
	GO: 0044391	Ribosomal subunit	1.52E − 03
	GO: 0005753	Mitochondrial proton-transporting ATP synthase complex	1.70E − 03
	GO: 0045259	Proton-transporting ATP synthase complex	2.52E − 03
	GO: 0016469	Proton-transporting two-sector ATPase complex	2.57E − 03
	GO: 0044455	Mitochondrial membrane part	3.11E − 03
Molecular function	GO: 0015078	Hydrogen ion transmembrane transporter activity	1.90E − 04
	GO: 0004129	Cytochrome-c oxidase activity	4.00E − 04
	GO: 0015002	Heme-copper terminal oxidase activity	4.00E − 04
	GO: 0016676	Oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	4.00E − 04
	GO: 0008553	Hydrogen-exporting ATPase activity, phosphorylative mechanism	4.19E − 04
	GO: 0016675	Oxidoreductase activity, acting on a heme group of donors	4.55E − 04
	GO: 0030515	snoRNA binding	3.03E − 03
	GO: 0036442	Hydrogen-exporting ATPase activity	3.79E − 03
	GO: 0016830	Carbon-carbon lyase activity	3.95E − 03
	GO: 0016814	Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4.66E − 03
	GO: 0000062	Fatty-acyl-CoA binding	6.17E − 03
	GO: 0019783	Ubiquitin-like protein-specific protease activity	6.26E − 03
	GO: 0019843	rRNA binding	3.21E − 02

22 GO terms are significantly enriched by the 289 changed genes after model group treated with ZGW rat serum.