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. 2018 Jul 6;12:381–392. doi: 10.1016/j.omtn.2018.05.020

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© 2018 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Effect of linc00473 on Trophoblast Migration, Invasion, and Vascularization In Vitro

(A–C) The migration and invasion capacity of cultured trophoblasts transfected with si-linc00473 in HTR-8/SVneo cells (A) or pcDNA3.1-linc00473 in JAR (B) and JEG3 (C) cells were analyzed by the Transwell assays and were significantly lower or higher, respectively, than that of control cells. (D) The number of branch points and total branching length of the network were decreased in si-linc00473-transfected HTR-8/SVneo cells and HUVECs compared to control cells. The data are presented as the mean ± SD of three independent experiments; **p < 0.01.