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The effect of Cry1 knockdown on mRNA levels of clock genes in Hos and U2os cells. A. and B. mRNA levels of Cry2, Per1, Per2, Per3, Bmal1 and Clock were upregulated, while Dec1, Dec2, CK1ε and Npas2 were downregulated. There were no differences in mRNA levels of Rev-Erbα and Rorα. Data are expressed as the mean ± standard deviation. *P<0.05 vs. the control.
