Table 2.

Comparison of Accuracy in ROP Diagnosis Between Telemedicine and Ophthalmoscopy

		Zone		Stage		Plus Disease		Category
Examination	No.	RSD Agreement, % (95%CI)	Weighted κ	RSD Agreement, % (95%CI)	Weighted κ	RSD Agreement, % (95%CI)	Weighted κ	RSD Agreement, % (95%CI)	Weighted κ
Telemedicine
Grader 1	1553	88 (87–90)	0.56	70 (68–73)	0.70	93 (92–94)	0.82	72 (70–74)	0.68
Grader 2	1553	87 (85–88)	0.48	71 (69–73)	0.69	87 (85–89)	0.68	73 (71–76)	0.70
Grader 3	1553	89 (88–91)	0.60	85 (84–87)	0.85	97 (96–98)	0.91	86 (85–88)	0.85
P valuea	NA	.06	NA	<.001	NA	<.001	NA	<.001	NA
Ophthalmoscopy
Clinician 1	616	95 (93–97)	0.83	94 (92–96)	0.91	95 (94–97)	0.86	94 (92–96)	0.91
Clinician 2	162	96 (93–99)	0.91	88 (83–94)	0.86	78 (71–84)	0.57	81 (75–87)	0.75
Clinician 3	82	94 (89–99)	0.89	77 (68–86)	0.69	72 (62–82)	0.13	77 (68–86)	0.68
Clinician 4	172	97 (95–99)	0.83	89 (85–94)	0.76	97 (95–99)	0.70	92 (88–96)	0.82
Clinician 5	446	86 (83–90)	0.63	82 (78–86)	0.70	82 (78–85)	0.17	71 (66–75)	0.51
P valuea	NA	<.001	NA	<.001	NA	<.001	NA	<.001	NA

Abbreviations: NA, not applicable; ROP, retinopathy of prematurity; RSD, reference standard diagnosis.

^aBased on Pearson χ² test.