Table 2.
Univariable and multivariable logistic analyses of factors associated with receipt of adjuvant therapy
| Univariable | Multivariable | |||||
|---|---|---|---|---|---|---|
| OR | (95% CI) | P value | OR | (95% CI) | P value | |
| Age | ||||||
| ≤65 | Ref | Ref | ||||
| >65 | 0.35 | 0.26–0.47 | <0.001 | 0.37 | 0.27–0.53 | <0.001 |
| Male Sex | 1.01 | 0.75–1.36 | 0.926 | |||
| Tumor Size | 1.17 | 1.11–1.24 | <0.001 | 1.07 | 1.01–1.14 | 0.023 |
| Site | ||||||
| Non-GEJ | Ref | |||||
| Gastro-Esophageal Junction (GEJ) | 1.14 | 0.65–1.99 | 0.65 | |||
| Histologic Grade | ||||||
| Well to Moderate | Ref | Ref | ||||
| Moderate to Poor | 2.82 | 2.02–3.93 | <0.001 | 1.53 | 1.05–2.23 | 0.027 |
| T stage | ||||||
| 1–2 | Ref | Ref | ||||
| 3–4 | 3.86 | 2.80–5.31 | <0.001 | 1.83 | 1.20–2.78 | 0.005 |
| Margin | ||||||
| R0 | Ref | Ref | ||||
| R1 | 2.5 | 1.34–4.68 | 0.004 | 1.27 | 0.62–2.60 | 0.515 |
| LNR | ||||||
| ≤0.25 | Ref | Ref | ||||
| >0.25 | 3.88 | 2.77–5.43 | <0.001 | 2.42 | 1.60–3.66 | <0.001 |
| Lymphovascular Invasion | 2.27 | 1.64–3.15 | <0.001 | 1.55 | 1.04–2.32 | 0.033 |
| Perineural Invasion | 2.03 | 1.39–2.99 | <0.001 | 0.97 | 0.61–1.53 | 0.886 |
| Operation type | ||||||
| Partial resection | Ref | |||||
| Total resection | 1.16 | 0.86–1.56 | 0.334 | |||
| Extent of Lymphadenectomy | ||||||
| D0/D1 | Ref | Ref | ||||
| D2/D3 | 2.1 | 1.55–2.86 | <0.001 | 2.45 | 1.71–3.51 | <0.001 |