Table 2.

Mixed model results for change in scale scores for the entire sample and by dose group, with corresponding effect sizes.

	Mean (std) change all	p all	Effect size	Mean (std) change 4 KKW	p 4 KKW	Effect size	Mean (std) change 16 KKW	p 16 KKW	Effect size	p between groups
Baseline to week 6
SHAPS	−0.81(2.61)	0.005	0.311	−1.02 (2.83)	0.020	0.361	−0.58 (2.35)	0.130	0.244	0.434
MEI total	9.96(15.99)	< 0.001	0.623	9.59(14.49)	< 0.001	0.662	10.41(17.77)	< 0.001	0.586	0.803
MEI ME	4.74(8.30)	< 0.001	0.570	4.57 (7.48)	< 0.001	0.612	4.93 (9.28)	0.001	0.531	0.832
MEI PE	1.82(4.12)	< 0.001	0.442	1.71 (4.15)	0.003	0.412	1.96 (4.12)	0.003	0.474	0.768
MEI SM	2.96(5.41)	< 0.001	0.547	2.83 (4.90)	0.001	0.490	3.11 (6.02)	0.001	0.516	0.801
Baseline to week 12
SHAPS	−1.19 (2.93)	0.001	0.406	−1.21 (2.78)	0.017	0.400	−1.17 (2.88)	0.013	0.406	0.958
MEI total	16.08 (19.49)	< 0.001	0.825	15.10 (16.06)	< 0.001	0.807	17.14 (20.48)	< 0.001	0.837	0.616
MEI ME	7.56 (9.73)	< 0.001	0.778	6.92 (8.33)	< 0.001	0.773	8.27 (10.56)	< 0.001	0.782	0.505
MEI PE	2.87 (4.86)	< 0.001	0.591	2.67 (3.88)	0.001	0.521	3.09 (4.58)	< 0.001	0.675	0.809
MEI SM	4.81 (6.44)	< 0.001	0.746	4.65 (5.37)	< 0.001	0.699	4.98 (6.28)	< 0.001	0.793	0.685