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. 2018 Jun 7;8(13):3571–3583. doi: 10.7150/thno.25194

Table 1.

Effect of Transcription factor AP-4 on the tumorigenicity of hepatocellular carcinoma cells in vivo (n = 10/group).

Cell type Cell number Tumor incidence TIC Frequency (95% CI) P value
HepG2-Vector 1000000 10/10 1/40,070
(1/79,901-1/20,095)
100000 7/10
10000 5/10
1000 3/10
100 0/10 < 0.01
HepG2-TFAP4 1000000 10/10 1/12025
(1/26,124-1/5,535)
100000 9/10
10000 7/10
1000 5/10
100 2/10
HepG2-RNAi-vector 1000000 10/10 1/28,214
(1/5,8953-1/13,503)
100000 8/10
10000 6/10
1000 3/10
100 0/10 < 0.05
HepG2-TFAP4-RNAi#1 1000000 10/10 1/65,094
(1/129,823-1/3,2638)
100000 6/10
10000 4/10
1000 1/10
100 0/10
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