Table 1.
Characteristics of NSCLC cases, by sex and smoking status (n = 813)
| Characteristic | Male, never smoker | Male, ever smoker | Female, never smoker | Female, ever smoker | ||
|---|---|---|---|---|---|---|
| No. (%) | No. (%) | No. (%) | No. (%) | P*, males | P*, females | |
| Total | 45 (100.0) | 318 (100.0) | 162 (100.0) | 288 (100.0) | ||
| Age, y | .006 | .05 | ||||
| <55 | 12 (28.6) | 31 (10.0) | 29 (19.0) | 47 (16.7) | ||
| 55–64 | 8 (19.0) | 85 (27.5) | 38 (24.8) | 70 (24.9) | ||
| 65–74 | 12 (28.6) | 119 (38.5) | 46 (30.1) | 116 (41.3) | ||
| 75+ | 10 (23.8) | 74 (24.0) | 40 (26.1) | 48 (17.1) | ||
| Ethnicity | .22 | .005 | ||||
| Hispanic | 0 (0.0) | 10 (3.3) | 12 (7.9) | 6 (2.2) | ||
| Non-Hispanic | 44 (100.0) | 290 (96.7) | 140 (92.1) | 268 (97.8) | ||
| Unknown | 1 | 18 | 10 | 14 | ||
| Race | <.001 | <.001 | ||||
| White | 37 (82.2) | 280 (88.1) | 119 (73.5) | 267 (92.7) | ||
| Black | 0 (0.0) | 15 (4.7) | 8 (4.9) | 11 (3.8) | ||
| Asian | 8 (17.8) | 9 (2.8) | 26 (16.0) | 3 (1.0) | ||
| Other | 0 (0.0) | 14 (4.4) | 9 (5.6) | 7 (2.4) | ||
| Family history of lung cancer | .17 | .38 | ||||
| Yes | 8 (17.8) | 84 (27.4) | 38 (24.1) | 79 (27.9) | ||
| No | 37 (82.2) | 223 (72.6) | 120 (75.9) | 204 (72.1) | ||
| Unknown | 0 | 11 | 4 | 5 | ||
| Histology | <.001 | <.001 | ||||
| Adenocarcinoma | 35 (77.8) | 134 (42.3) | 135 (83.9) | 161 (56.1) | ||
| Large cell | 1 (2.2) | 22 (6.9) | 1 (0.6) | 28 (9.8) | ||
| Other NSCLC | 0 (0.0) | 30 (9.5) | 7 (4.3) | 12 (4.2) | ||
| Squamous cell carcinoma | 3 (6.7) | 122 (38.5) | 3 (1.9) | 72 (25.1) | ||
| Bronchioloalveolar carcinoma | 6 (13.3) | 9 (2.8) | 15 (9.3) | 14 (4.9) | ||
| Unknown | 0 | 1 | 1 | 1 | ||
| Stage | .76 | .69 | ||||
| IA | 15 (34.9) | 91 (28.9) | 63 (39.4) | 120 (42.0) | ||
| IB | 14 (32.6) | 100 (31.7) | 51 (31.9) | 84 (29.4) | ||
| IIA | 4 (9.3) | 22 (7.0) | 7 (4.4) | 21 (7.3) | ||
| IIB | 3 (7.0) | 41 (13.0) | 19 (11.9) | 27 (9.4) | ||
| IIIA | 6 (14.0) | 44 (14.0) | 12 (7.5) | 24 (8.4) | ||
| IIIB | 1 (2.3) | 17 (5.4) | 8 (5.0) | 10 (3.5) | ||
| Unknown | 2 | 3 | 2 | 2 |
*
Ever vs never smokers, chi-square test (two-sided). NSCLC = non–small cell lung cancer.