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. 2018 Feb 20;110(7):768–776. doi: 10.1093/jnci/djx268

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© The Author(s) 2018. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 3. — Associations between tumor-infiltrating lymphocytes (TILs), genomic and transcriptomic features in the retrospective invasive lobular carcinoma (ILC) cohort. Univariate and multivariable associations between TIL and recurrently mutated genes (n = 399) (A) or recurrent copy number aberrations (n = 166) (B). Heatmap of the genes statistically significantly associated with TILs at the transcriptomic level (C). Correlation matrix of the lobular immune gene expression signature (ILC TIL) with published immune signatures (D). CNA = copy number aberration; ILC = invasive lobular carcinoma; TIL = tumor-infiltrating lymphocyte.