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. 2018 Jul 3;11:915–925. doi: 10.2147/IDR.S164262

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© 2018 de Altariis et al. This work is published and licensed by Dove Medical Press Limited

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Quantitative RT-PCR analysis of Candida albicans biofilm-related genes after AuNPs–indolicidin treatment after 24 h for C1 (A) and C5 (B) and after 48 h for C1 (C) and C5 (D). The relative levels of gene expression are presented as fold changes in AuNPs–indolicidin-treated groups (gray columns) with respect to the untreated controls (black columns). All gene transcript levels were normalized against ACT1 gene expression. Statistically significant differences between AuNPs–indolicidin-treated and untreated groups: *p<0.05 (Student’s t-test).

Abbreviations: RT-PCR, reverse transcription polymerase chain reaction; AuNPs, gold nanoparticles; C1, Candida albicans strain isolated from central venous catheter; C5, C. albicans strain ATCC 90028; AuNPs, gold nanoparticles.