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. Author manuscript; available in PMC: 2018 Jul 9.
Published in final edited form as: Anal Bioanal Chem. 2011 May 4;401(1):17–27. doi: 10.1007/s00216-011-5003-6

Fig. 2.

Fig. 2

Comparison of MALDI-IMS data in frozen and universal molecular fixative (UMFix)-processed tissue in a pair of matched prostate tissue samples. A tissue sample was harvested from a prostate surgery specimen and bisected. One half was snap-frozen (left) and the other was treated with UMFix (right). Top panels: Representative spectra of the m/z 4,355 ion. Middle panels: MALDI-IMS map showing high expression of m/z 4,355 in specific areas where tumor cells are located (circled) in the H&E staining image (bottom panel)