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Targeted MALDI-IMS for prostate-specific antigen (PSA). a. Resulting image from targeted IMS (TIMS) of prostate tissue showing the spatial distribution of the trityl tag (m/z 519.5) (left panel) which was bound to PSA in areas which also stained for PSA in traditional IHC for PSA (right panel) in a serial section. b. Resulting reflectron mode spectrum after release of the mass tag from the antibody by the MALDI laser
