Table 2.
Performance Status, Quality-of-Life, and Depression Scores and End-of-Life Outcomes
| Hematologic malignancy (n = 101) | Solid malignancy (n = 46) | Total (n = 147) | p | |
|---|---|---|---|---|
| Karnofsky performance status, mean (SD) | 63.0 (21.8) | 64.5 (21.3) | 63.3 (21.6) | 0.75 |
| Modified Charlson comorbidity index | ||||
| 0 | 30 (40.5%) | 17 (65.4%) | 47 (47.0%) | 0.03 |
| 1 | 9 (40.5%) | 4 (15.4%) | 13 (13.0%) | |
| 2 | 20 (27.0%) | 1 (3.8%) | 21 (21.0%) | |
| ≥3 | 15 (20.3%) | 4 (15.4%) | 19 (19.0%) | |
| Missing | 27 | 20 | 47 | |
| Physical, mean (SD) | 14.6 (6.7) | 12.9 (6.2) | 14.1 (6.5) | 0.17 |
| Social, mean (SD) | 24.6 (3.7) | 23.4 (3.9) | 24.2 (3.8) | 0.05 |
| Emotional, mean (SD) | 15.6 (2.1) | 15.0 (2.3) | 15.4 (2.2) | 0.26 |
| Functional, mean (SD) | 13.1 (5.1) | 13.9 (4.5) | 13.4 (4.9) | 0.49 |
| FACT-G, mean (SD) | 67.7 (11.2) | 65.1 (10.4) | 66.9 (11.0) | 0.18 |
| FACIT-spirituality subscale, mean (SD) | 39.6 (7.3) | 37.8 (7.0) | 39.1 (7.2) | 0.10 |
| Depression, mean (SD) | 3.0 (1.0, 6.0) | 4.0 (2.0, 6.5) | 3.0 (1.0, 6.0) | 0.11 |
| Depression score ≥4a | 28/101 (27.7%) | 17/46 (36.9%) | 45/147 (30.6%) | 0.26 |
| End-of-life outcomes | ||||
| Correctly estimate patient would die within next 12 months | 69 (68.3%) | 32 (69.6%) | 101 (68.7%) | 0.88 |
| DNR during index admission | 21 (20.8%) | 6 (13.0%) | 27 (18.4%) | 0.26 |
| DNR during subsequent admission | 44 (55.7%) | 18 (45.0%) | 62 (52.1%) | 0.27 |
| Missing | 22 | 6 | 28 | |
| Died in hospital during index admission | 12 (11.9%) | 0 (0.00%) | 12 (8.2%) | 0.01 |
| Died in hospital during subsequent admission | 37 (46.3%) | 14 (36.8%) | 51 (43.2%) | 0.33 |
| Missing | 21 | 8 | 29 | |
| Palliative care consultation during any hospitalization | 2 (2.0%) | 2 (4.3%) | 4 (2.7%) | 0.41 |
| Hospice before death | 21 (20.8%) | 16 (34.8%) | 37 (25.2%) | 0.07 |
a
Indicates high risk of depression.
DNR, do-not-resuscitate order.