. Author manuscript; available in PMC: 2018 Jul 9.

Published in final edited form as: Curr Opin Virol. 2017 Jul 3;24:132–139. doi: 10.1016/j.coviro.2017.06.009

Table 1.

Amino acid alignment of furin cleavage sites of different flaviviruses

Virus	Strain	Sequence pr		Sequence M	GenBank Accession no.
		`P14^a` `P1`		`P1‘^b` `P6‘`
DENV-1	SG/07K3640DK1/2008	`GTC-SQTGEHRRDKR`	↓^C	`SVALAPH`	GQ398255
DENV-2	16681	`GTC-TTMGEHRREKR`	↓	`SVALVPH`	U87411
DENV-3	SG/05K863DK1/2005	`GTC-NQAGEHRRDKR`	↓	`SVALAPH`	EU081190
DENV-4	SG/06K2270DK1/2005	`GTC-TQNGERRREKR`	↓	`SVALTPH`	GQ398256
ZIKV	H/PF/2013	`GTCHHKKGEARRSRR`	↓	`AVTLPSH`	KJ776791
WNV	NY_99	`GRC-TKTRHSRRSRR`	↓	`SLTVQTH`	KC407666
YFV	Asibi	`GKC-DSAGRSRRSRR`	↓	`AIDLPTH`	AY640589
TBEV	Neudoerfl	`GRCGKQEGS--RTRR`	↓	`SVLIPSH`	U27495

Amino acid sequence positions 1 to 14 (dengue virus numbers) upstream of cleavage site (pr part), position 3 (P3) in bold letters

Amino acid sequence positions 1 to 6 downstream of cleavage site (protein M)

The arrow indicates the proteolytic cleavage site.