Cluster 1 |
Enrichment Score: 8.96 |
|
|
|
Category |
Term |
P Value |
Genes |
Fold Enrichment |
INTERPRO |
Propeptide, peptidase A1 (IPR012848) |
2.45E-13 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG19, PAG20, |
14.36 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405, MGC157408
|
|
INTERPRO |
Peptidase A1 (IPR001461) |
1.35E-12 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG19, PAG20, |
13.02 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405, MGC157408
|
|
INTERPRO |
Aspartic peptidase (IPR021109) |
1.48E-11 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG19, PAG20, |
11.26 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405, MGC157408
|
|
GOTERM_MF_DIRECT |
Aspartic-type endopeptidase activity (GO:0004190) |
1.22E-10 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG19, PAG20, |
9.76 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405, MGC157408
|
|
INTERPRO |
Peptidase aspartic, active site (IPR001969) |
2.00E-10 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG20, |
12.03 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405
|
|
UP_KEYWORDS |
Aspartyl protease |
2.08E-10 |
PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG20, |
12.00 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405
|
|
GOTERM_BP_DIRECT |
Protein catabolic process (GO:0030163) |
2.15E-09 |
PAG1, PAG4, PAG7, PAG15, PAG16, PAG17, PAG18, PAG20, |
8.97 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405
|
|
GOTERM_BP_DIRECT |
Proteolysis (GO:0006508) |
0.0002 |
GGH, PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, PAG20, |
2.83 |
|
|
|
PAG21, LOC504812, LOC614287, MGC157405, PROZ, TPP2
|
|
UP_KEYWORDS |
Protease |
0.0002 |
CASP8, CLPP, CTSB, CTSC, CTSZ, ECE2, F7, F10, PAG1, PAG4, PAG5, PAG7, PAG15, PAG16, PAG17, PAG18, |
2.27 |
|
|
|
PAG19, PAG20, PAG21, PARL, NPEPL1, USP4, USP14, TPP2, LOC504812, LOC614287, MGC157405
|
|
Cluster 2 |
Enrichment Score: 2.03 |
|
|
|
Category |
Term |
P Value |
Genes |
Fold Enrichment |
SMART |
DEFSN (SM00048) |
0.0005 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD
|
12.18 |
INTERPRO |
Beta defensin/Neutrophil defensin (IPR006080) |
0.0006 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD
|
11.57 |
INTERPRO |
Beta defensin type (IPR001855) |
0.0012 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD
|
9.92 |
UP_KEYWORDS |
Defensin |
0.0061 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD
|
6.59 |
UP_KEYWORDS |
Antibiotic |
0.0204 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD, PENK
|
3.78 |
UP_KEYWORDS |
Antimicrobial |
0.0445 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD, PENK
|
3.08 |
GOTERM_BP_DIRECT |
Defense response to bacterium (GO:0042742)
|
0.073291513 |
DEFB1, DEFB4A, DEFB5B, DEFB10, EBD, NOS2, PENK
|
2.38 |
Annotation Cluster 3 |
Enrichment Score: 1.54 |
|
|
|
Category |
Term |
P Value |
Genes |
Fold Enrichment |
UP_KEYWORDS |
Microtubule |
0.0052 |
AURKA, DYNLL2, DYNLRB2, HAUS1, KATNAL2, KIF20A, NDRG1, REEP4, SKA1, |
2.68 |
|
|
|
TUBB1, TUBB4A, TUBGCP3
|
|
UP_KEYWORDS |
Cytoskeleton |
0.0485 |
AURKA, CETN1, CETNNA1, DAG1, DMTN, DYNLL2, DYNLRB2, FAM110B, FER, HAUS1, KATNAL2, |
1.55 |
|
|
|
KIF20A, MAP6D1, NDRG1, PDLIM2, PPP2CA, REEP4, RHOA, ROCK1, SKA1, TUBB1, TUBB4A, TUBGCP3
|
|
GOTERM_CC_DIRECT |
Microtubule (GO:0005874)
|
0.0968 |
DYNLL2, DYNLRB2, HAUS1, KATNAL2, KIF20A, NDRG1, REEP4, SKA1, MAP6D1
|
1.83 |
|
|
|
TUBB1, TUBB4A
|
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