Figure 3.

Pathway network representation of the metabolite-based enriched pathways for the 34 metabolites associated with low vs. high liver and kidney disease severity. Nodes correspond to significant pathways, with node size associated with the number of significant metabolites in each pathway; edges indicate common metabolites between two pathways. We identified significant groups of processes including a) polyamine metabolism and amino acid; b) purine metabolism, pyrimidine metabolism, and nucleotides.