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. Author manuscript; available in PMC: 2018 Jul 9.
Published in final edited form as: Hepatology. 2016 Jun 3;64(3):853–864. doi: 10.1002/hep.28570

Figure 6.

Figure 6

(A) Fasting gallbladder volumes as a function of days on the lithogenic diet. (B) Cholesterol and cholesteryl ester concentrations in the gallbladder tissues after 56 days of the lithogenic diet feeding. (C) Postprandial gallbladder emptying rates in response to duodenal infusion of corn oil or exogenously administered CCK-8 via intravenous injection (as indicated by the arrows) during the early stage of gallstone formation in mice fed the lithogenic diet for 14 days. Gallbladder emptying was impaired in WT, ABCG5(−/−)/G8(−/−), and ABCG8 (−/−) mice. (D) The mRNA levels of the genes involved in gallbladder lipid metabolism and transporters. See text for further description.