Table 3.
Cost parameter inputs used in the model.
| Cost category | Cost, € | Ref |
|---|---|---|
| TIV ex-factory pricea | 5.35 | 31 |
| MF59-TIV ex-factory price | 6.99 | |
| ID-TIV ex-factory price | 6.99 | |
| QIV ex-factory price | 11.08 | |
| Vaccine administration | 6.16 | 75 |
| GP visit | 20.66 | 74 |
| Outpatient treatment of complications (except for otitis media) | 80 | 76 |
| Outpatient treatment of otitis media | 50 | 76 |
| Bronchitis (DRG 097) | 1,832 | 31, 77 |
| Pneumonia (DRG 090) | 2,291 | 31, 77 |
| URTI (DRG 080) | 4,422 | 31, 77 |
| Cardiovascular complications (weighted mean DRGs) | 3,544 | 17 |
| Renal complications (DRG 316) | 3,734 | 31, 77 |
| CNS complications (weighted mean DRGs) | 3,507 | 17 |
| Otitis media (DRG 069) | 1,247 | 31, 77 |
| GI bleeding (DRG 175) | 2,091 | 31, 77 |
a
The ex-factory price of TIV is a weighted (by the volume sold) average of the available brands in Italy.
Abbreviations: CNS, central nervous system; DRG. Diagnosis related group; GI, gastrointestinal; GP, general practitioner; ID-TIV, intradermal trivalent inactivated vaccine; MF59-TIV, MF59-adjuvanted trivalent inactivated vaccine; QALY, quality-adjusted life year; QIV, quadrivalent inactivated vaccine; URTI, unspecified respiratory tract infection.