Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Feb 22;14(6):1417–1422. doi: 10.1080/21645515.2018.1433970

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Transgene. Published with license by Taylor & Francis

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

PMC Copyright notice

Figure 1. — Responder mice were defined as a mouse displaying a decrease in HBV-DNA (viremia), circulating HBsAg levels or both together higher than 0.5 log from baseline value for two or more time points during the study. (A) Overall response rate in seven experiments (mean percentage from 7 individual experiments). P-values for responders in TG1050 treated (red) and not-treated (blue) mice are shown above the graph. The increase in the chance (odd-ratio) to present a response (decrease in viremia, HBsAg or both) when treated with TG1050 is shown below the graph. (B) Circulating HBsAg levels before treatment in non-responder (NR) and responder mice (R), for viremia (left) or HBsAg (right). Values of individual mice from all 7 seven experiments are analyzed together. N is the number of mice analyzed in each bar. The median is indicated by a horizontal line, the mean by a big circle. P-values for responders versus non-responders are shown above the plots.