1.

Patients’ clinicopathological characteristics (N=114)

Variables	CCC (n=43)	GCC (n=20)	SC (n=16)	CHC (n=35)	P
HBV, hepatitis B virus; AFP, alpha-fetoprotein; CEA, carcinoembryonic antigen; LN, lymph node; CCC, clear cell carcinoma; GCC, giant cell carcinoma; SC, sarcomatoid carcinoma; CHC, combined hepatocellular-cholangiocarcinoma.
Age	57±12	57±9	56±6	52±10	0.161
Gender
Female	10	3	2	6	0.809
Male	33	17	14	29
Symptomatic	27	12	10	18	0.767
HBV infection	38	15	12	30	0.419
AFP>20 (ng/mL)	32	11	12	18	0.117
CEA>5 (ng/mL)	0	1	1	2	0.279
Cirrhosis	28	13	10	24	0.976
Size of tumor (cm)	4.3±2.0	5.5±4.2	6.3±2.6	5.8±2.7	0.043
Number of tumor
Solitary	38	16	12	26	0.361
Multiple	5	4	4	9
LN metastasis
(+)	0	0	2	3	0.040
(−)	43	20	14	32
Tumor embolus
(+)	3	7	8	10	0.001
(−)	40	13	8	25
Adjacent organ invasion
(+)	0	1	3	1	0.013
(−)	43	19	13	34
Pseudocapsule formation
(+)	20	2	1	3	0.001
(−)	23	18	15	32
Resection extent
R0	41	18	12	25	0.018
R1	2	2	4	10