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S2.

Clinicopathological characteristics of total TNBC patients (N=75)

Characteristics n (%)
TNBC, triple-negative breast cancer.
Age at diagnosis (year)
 ≤45 28 (37.3)
 >45 47 (62.7)
 Unknown 0
Histology of primary tumor
 Ductal 70 (94.6)
 Lobular 1 (1.4)
 Others 3 (4.1)
 Unknown 1
Initial tumor grade
 I 1 (2.1)
 II 28 (58.3)
 III 19 (39.6)
 Unknown 27
Initial TNM stage
 I 6 (9.1)
 II 24 (36.4)
 III 28 (42.4)
 IV 8 (12.1)
 Unknown 9
Family history
 Yes 8 (10.7)
 No 67 (89.3)
 Unknown 0
Sites of metastases at inclusion
 Chest 20 (26.7)
 Lymph node 49 (65.3)
 Bone 27 (36.0)
 Lung 27 (36.0)
 Liver 21 (28.0)
 Brain 9 (12.0)
 Unknown 0
Therapeutic status at inclusion
 First-line 50 (66.7)
 Second-line 15 (20.0)
 Third-line and beyond 4 (5.3)
 Stage IV at initial diagnosis 6 (8.0)