3.

Trend of incidence of laryngeal cancer in China, 2003–2012

Year	All				Urban				Rural
	Both (1/105)	Male (1/105)	Female (1/105)		Both (1/105)	Male (1/105)	Female (1/105)		Both (1/105)	Male (1/105)	Female (1/105)
APC, annual percentage change; 95% CI, 95% confidence interval; *, P<0.05 was considered statistically significant.
2003	1.49	2.70	0.36		1.63	2.97	0.38		0.97	1.69	0.29
2004	1.30	2.41	0.27		1.41	2.61	0.28		0.91	1.61	0.26
2005	1.49	2.65	0.40		1.66	2.96	0.43		0.80	1.36	0.29
2006	1.45	2.67	0.30		1.57	2.90	0.31		0.93	1.69	0.22
2007	1.43	2.63	0.29		1.58	2.90	0.31		0.79	1.45	0.16
2008	1.35	2.51	0.24		1.47	2.73	0.27		0.84	1.60	0.11
2009	1.41	2.63	0.24		1.55	2.91	0.26		0.79	1.45	0.15
2010	1.30	2.43	0.22		1.37	2.60	0.21		0.97	1.68	0.27
2011	1.32	2.48	0.21		1.43	2.71	0.21		0.84	1.51	0.20
2012	1.30	2.47	0.18		1.39	2.66	0.17		0.90	1.57	0.25
APC (%)	–1.27	–0.60	–7.09		–1.38	–1.01	–8.43		–0.36	–0.38	–1.55
95% CI (%)	–2.2, –0.3*	–1.6, 0.4	–10.3, –3.8*		–2.9, 0.2	–2.1, 0.1	–12.2, –4.4*		–2.3, 1.6	–2.1, 1.4	–5.9, 3.0