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2.

Baseline tumor subtype and pathology

Variable n (%)
All patients
(N=3,020)
Docetaxel/
anthracycline
combo (N=1,421)
Docetaxel/
anthracycline
sequential (N=447)
Docetaxel/other
(N=705)
Other
(N=447)
Tumor phase
 Stage 0 2 (0.1) 0 (0) 0 (0) 2 (0.3) 0 (0)
 Stage I 440 (14.6) 128 (9.0) 82 (18.3) 182 (25.8) 48 (10.7)
 Stage IIA 978 (32.4) 403 (28.4) 179 (40.0) 256 (36.3) 140 (31.3)
 Stage IIB 706 (23.4) 376 (26.5) 82 (18.3) 120 (17.0) 128 (28.6)
 Stage IIIA 604 (20.0) 350 (24.6) 64 (14.3) 98 (13.9) 92 (20.6)
 Stage IIIB 43 (1.4) 26 (1.8) 0 (0) 14 (2.0) 3 (0.7)
 Stage IIIC 223 (7.4) 127 (8.9) 36 (8.1) 29 (4.1) 31 (6.9)
 Unknown 10 (0.3) 3 (0.2) 2 (0.4) 1 (0.1) 4 (0.9)
 Data missing 14 (0.5) 8 (0.6) 2 (0.4) 3 (0.4) 1 (0.2)
Tumor type
 Ductal carcinoma 2,554 (84.6) 1,175 (82.7) 402 (89.9) 608 (86.2) 369 (82.6)
 Lobular carcinoma 101 (3.3) 72 (5.1) 9 (2.0) 17 (2.4) 3 (0.7)
 Medullary carcinoma 14 (0.5) 8 (0.6) 2 (0.4) 2 (0.3) 2 (0.4)
 Mixed carcinoma 37 (1.2) 16 (1.1) 4 (0.9) 10 (1.4) 7 (1.6)
 Mucinous carcinoma 12 (0.4) 6 (0.4) 3 (0.7) 2 (0.3) 1 (0.2)
 Tubular carcinoma 11 (0.4) 3 (0.2) 1 (0.2) 6 (0.9) 1 (0.2)
 Other 141 (4.7) 72 (5.1) 16 (3.6) 28 (4.0) 25 (5.6)
 Unknown 146 (4.8) 69 (4.9) 9 (2.0) 29 (4.1) 39 (8.7)
 Data missing 4 (0.1) 0 (0) 1 (0.2) 3 (0.4) 0 (0)
Tumor size (cm)
 <2 317 (28.6) 94 (22.5) 115 (28.4) 90 (39.8) 18 (30.5)
 ≥2 759 (68.6) 319 (76.5) 273 (67.4) 126 (55.8) 41 (69.5)
 Data missing 31 (2.8) 4 (1.0) 17 (4.2) 10 (4.4) 0 (0)
 NA* 1,913 1,004 42 479 388
Lymphovascular invasion
 Yes 140 (12.6) 50 (12.0) 55 (13.6) 24 (10.6) 11 (18.6)
 No 577 (52.1) 224 (53.7) 205 (50.6) 118 (52.2) 30 (50.8)
 Unknown 390 (35.2) 143 (34.3) 145 (35.8) 84 (37.2) 18 (30.5)
 NA* 1,913 1,004 42 479 388
Estrogen receptor
 Negative 1,088 (36.0) 487 (34.3) 184 (41.2) 234 (33.2) 183 (40.9)
 Positive 1,868 (61.9) 891 (62.7) 258 (57.7) 465 (66.0) 254 (56.8)
 Unknown 61 (2.0) 42 (3.0) 5 (1.1) 4 (0.6) 10 (2.2)
 Data missing 3 (0.1) 1 (0.1) 0 (0) 2 (0.3) 0 (0)
Progesterone receptor
 Negative 1,297 (42.9) 595 (41.9) 212 (47.4) 281 (39.9) 209 (46.8)
 Positive 1,654 (54.8) 781 (55.0) 230 (51.5) 416 (59.0) 227 (50.8)
Table 2 (continued)