Fig. 3. Results of rotational thromboelastometry. (A) Extrinsic pathway screening thromboelastometry (EXTEM) for CRF rats. (B) EXTEM for control rats. (C) Intrinsic pathway screening thromboelastometry (INTEM) for CRF rats. (D) INTEM for control rats. In EXTEM, the CRF group (A) showed a shorter time to clotting initiation [clotting time (black arrow), 59.0±7.3 s vs. 72.8±5.0 s, p=0.032] and a higher velocity to clot growth (α angle, 84.8±0.2° vs. 82.0±0.6°, p=0.008) than the control group (B). The clot formation time, MA10, and MA20 were not different between the two groups. However, in INTEM, the clotting time, clot formation time, α angle, MA10, and MA20 were not different between the CRF (C) and control groups (D).