Table 4.
Unique and shared activations for fear from a conjunction analysis across activations in the physical and social training groups.
| Brain Region | Brodmann Area | Cluster Volume | Max Intensity t | Voxel | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Unique Activations in the Physical Training Group | ||||||
| B caudate head | 770 | 9.72 | −1 | 21 | 10 | |
| B hypothalamus/pons/ thalamus/parahippocampus/ cerebellum/culmen | 552 | 8.63 | −1 | −31 | −6 | |
| R mid-temporal | 21 | 460 | 7.71 | 49 | −35 | −6 |
| L mid-temporal | 22 | 247 | 6.93 | −45 | −31 | 4 |
| R mid-frontal (eye fields) | 6 | 211 | 6.23 | 31 | 3 | 42 |
| R posterior insula/ | 7 | 203 | 8.51 | 45 | 1 | −8 |
| R STG | 21 | |||||
| L posterior occipital | 17/18 | 193 | 5.00 | −19 | −97 | −2 |
| R lOFC | 47 | 142 | 5.77 | 53 | 19 | −10 |
| L mid-cingulate gyrus | 24 | 111 | 6.34 | −17 | −11 | 34 |
| L med frontal gyrus | 6 | 105 | 5.76 | −9 | 7 | 54 |
| L precuneus | 7 | 90 | 6.00 | −3 | −77 | 42 |
| L mid-frontal (eye fields) | 6 | 72 | 5.22 | −39 | −1 | 48 |
| L cerebellum/culmen | 65 | 5.21 | −9 | −45 | −6 | |
| L parahippocampal gyrus/ culmen | 61 | 6.56 | −29 | −55 | 2 | |
| L OFC/STG | 47/38 | 55 | 5.18 | −45 | 13 | −6 |
| L insula | 13 | 51 | 4.59 | −41 | −7 | 0 |
| L postcentral gyrus | 43 | 38 | 4.80 | −51 | −17 | 16 |
| R insula | 13 | 24 | 5.68 | 37 | −23 | 16 |
| L inferior parietal | 40 | 20 | 5.16 | −41 | −37 | 22 |
| Unique Activations in the Social Training Group | ||||||
| R supramarginal gyrus | 40 | 6,143 | 7.36 | 13 | −73 | 34 |
| B precuneus | 7 | |||||
| angular gyrus | 39 | |||||
| occipital lobe | 18/19 | |||||
| fusiform gyrus cerebellum (declive, culmen) | 37 | |||||
| R posterior insula | 13 | 1,538 | 8.39 | 45 | −17 | −10 |
| STG | 21/22 | |||||
| L posterior insula | 13 | 1,051 | 8.16 | −63 | −41 | 18 |
| STG parahippocampus | 21/22 | |||||
| R IFC | 6/9 | 911 | 5.95 | 39 | 5 | 30 |
| L precentral gyrus | 6 | 331 | 5.41 | −43 | −9 | 42 |
| R thalamus (red nucleus, medial geniculum) | 131 | 5.37 | 9 | −23 | −4 | |
| L dlPFC | 10 | 94 | 8.53 | −35 | 55 | 24 |
| L mid-cingulate gyrus | 24 | 92 | 6.62 | −23 | −7 | 28 |
| R dlPFC | 10 | 89 | 5.64 | 35 | 43 | 14 |
| B precuneus | 7 | 81 | 5.37 | −3 | −49 | 52 |
| R mid-cingulate gyrus | 24 | 77 | 5.25 | 13 | 7 | 38 |
| B PCC | 23 | 72 | 5.09 | −5 | −31 | 28 |
| Shared Activations Between the Physical and Social Training Groups | ||||||
| R mid-temporal | 22 | 125 | 6.24 (7.38) | 43 (43) | −23 (−23) | −4 (−4) |
| R mid-frontal (eye fields) | 6 | 77 | 7.52 (4.90) | 31 (43) | 1 (1) | 42 (48) |
| L mid-temporal | 22 | 70 | 6.77 (5.67) | −47 (−47) | −31 (−25) | 4 (2) |
| L cingulate gyrus | 24 | 68 | 6.83 (8.13) | −23 (−23) | −15 (−5) | 32 (28) |
| R insula | 13 | 50 | 6.02 (7.18) | 47 (35) | −23 (−23) | 16 (16) |
| L precentral gyrus | 43 | 47 | 6.72 (4.66) | −59 (−59) | −7(−23) | 12 (18) |
| R thalamus | 40 | 5.06 (5.43) | 13 (11) | −25 (−25) | −4 (−2) | |
| L ACC | 32 | 38 | 7.66 (5.14) | −19 (−19) | 31 (31) | 4 (6) |
| R dlPFC | 9 | 38 | 4.31 (5.38) | 47 (41) | 17 (15) | 30 (26) |
| R supramarginal gyrus | 40 | 31 | 4.57 (5.40) | 55 (53) | −47 (−39) | 18 (16) |
| L insula | 13 | 21 | 4.36 (6.69) | −47 (−51) | −33 (−39) | 20 (18) |
Note. Activations were obtained using an independent voxel threshold of p < .005 and a cluster threshold of 60 voxels, in each of the two situation training groups. Clusters having 221 voxels or larger are significant at p < .05. Smaller clusters are shown to provide a sense of weaker activations. Clusters smaller than 60 voxels resulted from the conjunction analysis producing cluster fragments, when different parts of a cluster were shared vs. unique. Cluster fragments smaller than 20 voxels are not shown.
indicates a shared activation significant at the p<.05 extent threshold (221 voxels). R is right, L is left, B is bilateral, dlPFC is dorsolateral prefrontal cortex, STG is superior temporal gyrus, lOFC is lateral orbitofrontal cortex, and ACC is anterior cingulate cortex.