. Author manuscript; available in PMC: 2019 Sep 1.

Published in final edited form as: Clin Microbiol Infect. 2018 Jan 9;24(9):1016.e7–1016.e13. doi: 10.1016/j.cmi.2017.12.024

Table 2.

Genomic and phenotypic antibiogram of C. striatum isolates

Antibiotic Class Antibiotic Zone of Inhibition (mm)	CORYNE-1	CORYNE-2	CORYNE-3	CORYNE-4	CORYNE-5	CORYNE-6	CORYNE-7

Fluoroquinolones	gyrA mutation (S95T, D94A, E88A)	gyrA mutation (S95T, D94G, D87G)	gyrA mutation (S95T, D94G, D87G)	gyrA mutation (S95T, D94G, D87G)	gyrA mutation (S95T, D94G, D87G)	gyrA mutation (S95T, D94G, D87G)	gyrA mutation (S95T, D94A)

levofloxacin	6	6	6	6	6	6	6

Aminoglycosides	aac(3)-XI, aph(3″)-Ib, aph(6)-Id, aph(3′)-Ic	*aac(3)-XI*	*aac(3)-XI*	aac(3)-XI, aph(3″)-Ib, aph(6)-Id, aph(3′)-Ic		*aac(3)-XI*	aac(3)-XI

gentamicin	16	19	6	30	29	18	18

Phenicols	cmx			cmx

chloramphenicol	8	32	35	9	30	31	28

Macrolides	erm(X)	*erm(X)*	*erm(X)*	erm(X)	erm(X)	*erm(X)*	erm(X)

erythromycin	12	8	6	6	10	9	8

clindamycin	6	6	6	6	6	6	6

Tetracyclines	tet(W)	*tet(W)*	*tet(W)*		tet(W)	*tet(W)*	tet(W)

tetracycline	28	13	12	26	12	11	12

Beta-lactams	15	21	15	15	12	14	16
penicillin	15	21	15	15	12	14	16

penicillin	27	28	25	27	28	23	30

Other	23	25	31	25	23	24	24
vancomycin	23	25	31	25	23	24	24

sulfamethoxazole w/ trimethoprim	6	6	6	6	6	6	6

rifampin	36	36	40	36	34	36	36

linezolid	36	38	40	42	38	40	38

Kirby-Bauer disk diffusion testing. Bolded columns highlight the related sub-cluster of patient isolates CORYNE-2, -3, and -6.